Mechanism of Action
About Sandostatin LAR Depot
Sandostatin® LAR Depot (octreotide acetate) for injectable suspension has been designed to target somatostatin receptors. Octreotide exerts pharmacologic actions similar to those of the natural hormone somatostatin, but it is an even more potent inhibitor of growth hormone, glucagon, and insulin.1,2 Once it presents in the systemic circulation, octreotide distributes and exhibits a 3-phase pharmacokinetic profile.2-4
COMPLEX MICROSPHERE TECHNOLOGY
Sandostatin LAR Depot allows for longer dosing intervals by using a complex microsphere technology. Drug particles are encapsulated within a biodegradable microsphere polymer matrix, which slowly biodegrades in the muscle.3,4